Large-scale genetic study provides new insight into the causes of migraine

The study was based on DNA samples of 375,000 European, American and Australian participants. Almost 60,000 of them suffer from migraine.

The researchers combined data from 22 genome-wide association studies including new data from around 35,000 migraine sufferers. From the millions of genetic variants analyzed, 38 independent genomic regions were shown to be associated with migraine. Only ten of these regions have been implicated in migraine susceptibility before.

Original article: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine (2016). Padhraig Gormley, Verneri Anttila, Bendik S Winsvold et al. Nature Genetics. doi: 10.1038/ng.3598  http://dx.doi.org/10.1038/ng.3598