GWAS dataset	Cases	Controls	Reference
NatGen 2016 Any migraine	59 674	316 078	Gormley et al. NatGen 2016
NatGen 2016 MA only	6 332	144 883	Gormley et al. NatGen 2016
NatGen 2016 MO only	8 348	139 622	Gormley et al. NatGen 2016
NatGen 2013 Any migraine	23 285	95 425	Anttila et al. NatGen 2013
NatGen 2012 Clinical MO	2 326	4 580	Freilinger et al. NatGen 2012
NatGen 2010 Clinical MA	2 731	10 747	Anttila et al. NatGen 2010

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Cohorts (Population-based)

 

ALSPAC (The Avon Longitudinal Study of Parents and Children) 

Australian Twin cohort

B58C (British 1958 Birth Cohort)

ERF (The Erasmus Rucphen Family Study)

FinnTwin (Finnish Twin Cohort)

HUNT (The Nord-Trøndelag Health Study)

NTR (the Netherlands Twin Registry)

NESDA (the Netherlands Study of Depression and Anxiety)

NFBC (Northern Finland Birth Cohort)

The Rotterdam Study

Twins UK

The Women’s Genome Health Study (WGHS)

1000 Genomes

 

Hautakangas et al. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. 2021 medRxiv https://doi.org/10.1101/2021.01.20.21249647

Summary statistics with P < 5e-8

File of 8,117 SNPs (migraine_ihgc2021_gws_gwama.txt and README_migraine_ihgc2021_gws_gwama).

Genome-wide summary statistics for the four other study collections except 23andMe are available for bona fide researchers (contact Dr. Dale Nyholt, d.nyholt@qut.edu.au, for the link to data). The full GWAS summary statistics for the 23andMe discovery data set will be made available through 23andMe to qualified researchers under an agreement with 23andMe that protects the privacy of the 23andMe participants. Please visit research.23andme.com/collaborate/#publication for more information and to apply to access the data.