Datasets and Cohorts

 

GWAS dataset

Cases

Controls

Reference

NatGen 2016

Any migraine

59 674  316 078

Gormley et al.

NatGen 2016

NatGen 2016

MA only

6 332  144 883

Gormley et al.

NatGen 2016

NatGen 2016

MO only

8 348 139 622

Gormley et al.

NatGen 2016

NatGen 2013

Any migraine

23 285

95 425

Anttila et al.

NatGen 2013

NatGen 2012

Clinical MO

2 326 4 580

Freilinger et al.

NatGen 2012

NatGen 2010

Clinical MA

2 731  10 747

Anttila et al.

NatGen 2010

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Cohorts (Population-based)

 

ALSPAC (The Avon Longitudinal Study of Parents and Children) 

Australian Twin cohort

B58C (British 1958 Birth Cohort)

ERF (The Erasmus Rucphen Family Study)

FinnTwin (Finnish Twin Cohort)

HUNT (The Nord-Trøndelag Health Study)

NTR (the Netherlands Twin Registry)

NESDA (the Netherlands Study of Depression and Anxiety)

NFBC (Northern Finland Birth Cohort)

The Rotterdam Study

Twins UK

The Women’s Genome Health Study (WGHS)

1000 Genomes

 

Hautakangas et al. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. 2021 medRxiv https://doi.org/10.1101/2021.01.20.21249647

Summary statistics with P < 5e-8

File of 8,117 SNPs (migraine_ihgc2021_gws_gwama.txt and README_migraine_ihgc2021_gws_gwama).

Genome-wide summary statistics for the four other study collections except 23andMe are available for bona fide researchers (contact Dr. Dale Nyholt, d.nyholt@qut.edu.au, for the link to data). The full GWAS summary statistics for the 23andMe discovery data set will be made available through 23andMe to qualified researchers under an agreement with 23andMe that protects the privacy of the 23andMe participants. Please visit research.23andme.com/collaborate/#publication for more information and to apply to access the data.